Air Travel
- Companies: American Airlines, Delta Air Lines
 - Duration: Approximately 5 hours (including layovers)
 - Distance: 800 miles (approximately 1,287 kilometers)
 - Costs: €200 - €350 (one-way ticket, depending on the booking time and class)
 - Roads/Routes: Not applicable for air travel
 
Pro Tip: Consider booking directly through the airline's website for the best deals and for the option to choose your seat.
For a smooth journey from Clayton, NM to La Crosse, WI, flying is the most efficient option given that it minimizes travel time significantly. Use a local taxi service to reach Amarillo International Airport (approximately 1.5 hours drive) to catch a connecting flight.
Road Travel
- Companies: Personal Vehicle or Rent a Car (Enterprise, Hertz)
 - Duration: Approximately 12 hours (non-stop driving)
 - Distance: 760 miles (approximately 1,225 kilometers)
 - Costs: €120 - €160 (fuel costs based on average consumption), €50 - €100 (car rental fees for a single day)
 - Roads/Routes: US-87 N, I-25 N, I-90 E
 
Pro Tip: Plan your trip to include resting points, and make use of apps like Waze for real-time traffic updates and roadside assistance options.
For those opting to drive, taking the scenic routes via US-87 N and I-90 E can enhance your travel experience, allowing for stops at various attractions along the journey.
Bus Travel
- Companies: Greyhound, Megabus
 - Duration: Approximately 15 hours
 - Distance: 760 miles (approximately 1,225 kilometers)
 - Costs: €70 - €120 (one-way ticket)
 - Roads/Routes: Not applicable as this involves intercity routes
 
Pro Tip: Purchase tickets in advance online to secure your seat and often at a lower rate.
Traveling by bus is a budget-friendly option that can be slightly longer but offers an opportunity to sit back and enjoy the changing landscapes. Make sure to check for available amenities like Wi-Fi and power outlets on board.
Overall Recommendation
For the fastest and most efficient travel option, I recommend flying from Amarillo International Airport to a nearby large airport (like Minneapolis–Saint Paul International Airport) and then either booking a connecting flight to La Crosse Regional airport or opting for a rental car to complete your journey. However, for budget travelers or those who enjoy roadtripping, driving provides flexibility and the chance to explore more of the United States. Each option has its merits depending on your priorities—cost, time, or experience.