Via Air
- Companies: American Airlines, Delta Air Lines
 - Duration: Approximately 3 hours (including layovers)
 - Distance: 285 kilometers (approximately 177 miles)
 - Costs: Between €150 - €250 (depending on booking time and availability)
 - Roads/Routes: Not applicable
 
Pro Tip: Consider booking a flight that departs in the early morning for lower fares and less crowded airports.
For a straightforward and quick option, flying is recommended as it minimizes travel time and provides convenience, especially for such distance.
Via Train
- Companies: Amtrak (Northeast Regional)
 - Duration: Approximately 5 hours
 - Distance: 285 kilometers (approximately 177 miles)
 - Costs: Around €50 - €80 (depending on class and advance booking)
 - Roads/Routes: Amtrak's Northeast Corridor
 
Pro Tip: Book your tickets in advance and choose a window seat to enjoy the scenic views of the Northeast Corridor.
Taking the train offers a comfortable and scenic option to travel between Lowell and Philadelphia, with convenient access to city centers.
Via Bus
- Companies: Greyhound, Megabus
 - Duration: Approximately 7-8 hours
 - Distance: 285 kilometers (approximately 177 miles)
 - Costs: Approximately €25 - €45 (depending on the time of travel)
 - Roads/Routes: I-95 S
 
Pro Tip: Choose your bus trip carefully during off-peak times to ensure you get a less crowded experience and possibly lower fares.
For budget-conscious travelers, taking the bus is a viable option; however, expect the longest travel time compared to other transport modes.
Comprehensive Recommendation
The best option for this journey largely depends on your priorities: if time is of the essence, flying would be most efficient despite potentially higher costs. For a balance of comfort and cost, the train is an excellent choice, offering direct city-to-city services. For those on a budget, the bus is the most economical option, although it requires extra travel time.