Road Trip
- Transport Mode: Car
- Companies: Enterprise Rent-A-Car, Hertz
- Duration: Approximately 4 hours 30 minutes
- Distance: 270 miles
- Costs: Estimated $50-$70 for gas; rental costs vary (approximately $50-$100 per day); total around $100-$170
- Roads/Routes: I-35 S, I-44 S
Pro Tip: Download offline maps before starting your journey in case of poor signal areas to ensure you stay on track.
The best way to travel from Des Moines, IA to Neosho, MO is by car, allowing you to explore the scenic countryside along the way. Take I-35 S from Des Moines, then transition to I-44 S, which offers various rest stops and beautiful views. Make sure to check your vehicle's gas levels and plan for refueling as there may be stretches with fewer services.