Road Trip
- Companies: [Enterprise Rent-A-Car], [Hertz], [Avis]
- Duration: Approximately 6 hours
- Distance: 380 miles
- Costs: Estimated total: $150 (including rental and fuel) [subject to variation]
- Roads/Routes: I-55 S is the primary route taken from Chicago to Sikeston.
Pro Tip: Consider leaving early in the morning to avoid Chicago's rush hour traffic, and take periodic breaks to enjoy local attractions along the route, such as the Route 66 Museum in Pontiac, IL.
This road trip from Chicago to Sikeston is an enjoyable, straightforward journey. Renting a car gives you the flexibility to explore and take scenic detours if you desire. Make sure to check for any road work or traffic advisories before starting your journey.